Coffee May Increase Heart Attack Risk in Individuals with Gene Mutation

March 7, 2006

Individuals with a mutation of the liver enzyme that metabolizes caffeine appear to be at greater risk for heart attacks when they drink over four cups of coffee percoffee day compared with those who drink less than one cup according to a report in the Journal of the American Medical Association.

The team’s results showed that only carriers of the gene mutation for slow caffeine metabolism were at increased risk of heart attack associated with drinking coffee.

For these patients, the increased risk was 64 percent for four or more cups per day over the previous year compared with patients who drank less than one cup per day. The corresponding risk was less than 1 percent for subjects who had two copies of the rapid metabolizing gene.

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One Response to “Coffee May Increase Heart Attack Risk in Individuals with Gene Mutation”

  1. kalai Says:

    i need full information on carriers of the gene mutation for slow caffeine metabolism (i.e)which gene causes it

    the article is interesting to study and is usefull for the society


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